Article
[Simultaneous detection of polymorphisms in the 3'- and 5'-UTR of thymidylate synthase gene using denaturing high-performance liquid chromatography].
Yi chuan = Hereditas - 1 Mar 2007
Zhang Xiao-Mei, Chen Sen-Qing, Cao Hai-Xia, Wu Jian-Zhong, Ma Guo-Jian, Li Jin-Tian
Abstract excerpt
Polymorphism which is either in the thymidylate synthase (TS)enhancer region (TSER) of the 5-primer untranslation region (5' UTR) or in the 3-primer untranslation region (3' UTR) has been reported to be associated with the alterations in TS mRNA and protein levels. The TSER is characteristic of the presence of variable double (2R) and triple (3R) number tandem repeats (VNTRs). In addition to VNTRs, single...
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