Article
Genetic diversity of the DBLalpha region in Plasmodium falciparum var genes among Asia-Pacific isolates.
Molecular and biochemical parasitology - 1 Mar 2002
Fowler Elizabeth V, Peters Jennifer M, Gatton Michelle L, Chen Nanhua, Cheng Qin
Abstract excerpt
In Plasmodium falciparum a highly polymorphic multi-copy gene family, var, encodes the variant surface antigen P. falciparum erythrocyte membrane protein 1 (PfEMP1), which has an important role in cytoadherence and immune evasion. Using previously described universal PCR primers for the first Duffy binding-like domain (DBLalpha) of var we analysed the DBLalpha repertoires of Dd2 (originally from Thailand) and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
