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Article

Polymorphisms in transporter associated with antigen presenting are associated with cervical intraepithelial neoplasia and cervical cancer in a Chinese Han population.

HLA - 1 Jul 2021

Yang Jia, Liu Weipeng, Yan Zhiling, Li Chuanyin, Liu Shuyuan, Yang Xi, Li Yu, Shi Li, Yao Yufeng

Abstract excerpt

The host immune system plays an important role in infectious diseases and cancers. The heterodimer formed by transporter associated with antigen presenting (TAP)1 and TAP2 is responsible for intracellular peptide loading onto MHC-I molecules. Studies have shown that single-nucleotide polymorphisms (SNPs) in TAP genes might affect the expression and function of TAP and be associated with cancer risk. We aimed to...

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PMID: 34050605
DOI: 10.1111/tan.14333

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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