Article
Plasma neurofilament heavy chain levels in Huntington's disease.
Neuroscience letters - 7 May 2007
Wild Edward J, Petzold Axel, Keir Geoff, Tabrizi Sarah J
Abstract excerpt
There is a need for biomarkers of onset and progression in Huntington's disease (HD), as current outcome measures lack the reliability to enable the efficient conduct of disease-modifying trials. Neurofilament heavy chain (NfH) is a neuron-specific protein for the neuro-axonal compartment that has been proposed as a marker for axonal injury, degeneration and loss and its clinical use as a biomarker has been...
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