Article
Incidence of donor and recipient toll-like receptor-4 polymorphisms in kidney transplantation.
Transplantation proceedings - 1 Mar 2007
Nogueira E, Ozaki K S, Macusso G D, Quarim R F, Câmara N O S, Pacheco-Silva A
Abstract excerpt
UNLABELLED: Toll-like receptors (TLR) comprise an emerging family that recognize pathogen-associated molecular patterns and promote the activation of leukocytes. Recently, TLR has been demonstrated to play a role in experimental allograft rejection. However, the TLR-4 gene has a polymorphism that can be associated with a blunted immune response, especially to microbial pathogens. We sought to study the incidence...
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