Article
Toll-like receptor 4 and CD14 gene polymorphisms in Tunisian kidney transplantation.
Transplantation proceedings - 1 Jan 2013
Krichen H, Gorgi Y, Dhaouadi T, Mecheri Y, Sfar I, Bardi R, Bacha M M, Abderrahim E, Jendoubi-Ayed S, Ayed K, Ben Abdallah T
Abstract excerpt
BACKGROUND: Acute and chronic rejections remain an important cause of graft loss after renal transplantation. Currently, activation of innate immune responses through Toll-like receptors (TLRs) is suspected to be implied in the loss of the transplant tolerance. OBJECTIVES: We investigated functional single nucleotide polymorphisms (SNPs) of TLR4 and its coreceptor CD14 in kidney transplantation and looked for any...
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