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Article

Joint formation requires muscle formation and contraction.

Developmental cell - 1 May 2009

Yasuda Hideyo, de Crombrugghe Benoit

Abstract excerpt

Embryo movement and muscle contraction affect joint formation, but their precise roles have remained elusive. In this issue of Developmental Cell, Joy Kahn and coworkers now demonstrate that these processes are essential for joint formation. They find that joint progenitor cells are unable to remain committed to their specified cell fate in mutant mice with defects in either muscle formation or contraction.

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Source

Identifiers

PMID: 19460337
DOI: 10.1016/j.devcel.2009.05.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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