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Article

Assisted reproductive technologies do not alter mutation frequency or spectrum.

Proceedings of the National Academy of Sciences of the United States of America - 20 Mar 2007

Caperton Lee, Murphey Patricia, Yamazaki Yukiko, McMahan C Alex, Walter Christi A, Yanagimachi Ryuzo, McCarrey John R

Abstract excerpt

Assisted reproductive technologies (ARTs) have now contributed to the birth of >3 million babies worldwide, but concerns remain regarding the safety of these methods. We have used a transgenic mouse model to examine the effects of ARTs on the frequency and spectrum of point mutations in midgestation mouse fetuses produced by either natural reproduction or various methods of ART, including preimplantation culture,...

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Share to DNA Methylation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17360354
DOI: 10.1073/pnas.0611642104
PMCID: PMC1808421

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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