Article
Epigenetic regulation of genetic integrity is reprogrammed during cloning.
Proceedings of the National Academy of Sciences of the United States of America - 24 Mar 2009
Murphey Patricia, Yamazaki Yukiko, McMahan C Alex, Walter Christi A, Yanagimachi Ryuzo, McCarrey John R
Abstract excerpt
Cloning by somatic cell nuclear transfer (SCNT) circumvents processes that normally function during gametogenesis to prepare the gamete genomes to support development of new progeny following fertilization. One such process is enhanced maintenance of genetic integrity in germ cells, such that ger...
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