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Increased rate of <i>de novo</i> single nucleotide mutation in house mice born through assisted reproduction

2025-06-30

Abstract excerpt

<h4>ABSTRACT</h4> Approximately 2.6% of live births in the United States are conceived using assisted reproductive technologies (ARTs). While some ART procedures, including in vitro fertilization (IVF) and intracytoplasmic sperm injection, are known to alter the epigenetic landscape of early embryonic development, their impact on DNA sequence stability is unclear. Here, we leverage the strengths of the laboratory...

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Literature Corpus work
e5959dc7-5b06-54e1-b49f-564986c524cf
DOI
10.1101/2025.06.27.662069
Open publication

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Increased rate of <i>de novo</i> single nucleotide mutation in house mice born through assisted reproductionDOI 10.1101/2025.06.27.662069
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