Article
Transcriptional activation of the Listeria monocytogenes hemolysin gene in Bacillus subtilis.
Journal of bacteriology - 1 Feb 1992
Freitag N E, Youngman P, Portnoy D A
Abstract excerpt
The prfA gene of Listeria monocytogenes was recently reported to be required for expression of hly, which encodes a pore-forming hemolysin essential for pathogenicity (M. Leimeister-Wachter, C. Haffner, E. Domann, W. Goebel, and T. Chakraborty, Proc. Natl. Acad. Sci. USA 87:8336-8340, 1990). We demonstrate here that a hly-lacZ fusion introduced into Bacillus subtilis is strongly activated when the prfA gene...
Topics
- Bacillus subtilis
- Base Sequence
- Gene Expression Regulation, Bacterial
- Hemolysin Proteins
- Listeria monocytogenes
- Molecular Sequence Data
- Mutagenesis
- Mutation
- Promoter Regions, Genetic
- Recombinant Fusion Proteins
- Repetitive Sequences, Nucleic Acid
