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[Construction and characterization of Listeria monocytogenes deltaprfA mutant strains].

Wei sheng wu xue bao = Acta microbiologica Sinica - 4 Nov 2011

Bai Chunguang, Yin Yuelan, Jia Yanyan, Fu Hong, Gao Yunfei, Jiao Xin'an

Abstract excerpt

OBJECTIVE: Listeria monocytogenes (Lm) is an important pathogen that can cause serious listeriosis in humans and animals. The pathogenicity of Lm has a close relationship with the PrfA protein regulating the expression of virulence genes. Therefore, we studied the regulation functions of PrfA and its role on Lm's virulence. METHODS: The prfA genes of LM4, serotype 1/2a, and F4636, serotype 4b, were deleted by...

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PMID: 22260054

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