Article
Validation study of genetic associations with coronary artery disease on chromosome 3q13-21 and potential effect modification by smoking.
Annals of human genetics - 1 Nov 2009
Horne Benjamin D, Hauser Elizabeth R, Wang Liyong, Muhlestein Joseph B, Anderson Jeffrey L, Carlquist John F, Shah Svati H, Kraus William E
Abstract excerpt
The CATHGEN study reported associations of chromosome 3q13-21 genes (KALRN, MYLK, CDGAP, and GATA2) with early-onset coronary artery disease (CAD). This study attempted to independently validate those associations. Eleven single nucleotide polymorphisms (SNPs) were examined (rs10934490, rs16834817, rs6810298, rs9289231, rs12637456, , , , , , ) in patients (N =...