Article
Enduring vulnerability to reinstatement of methamphetamine-seeking behavior in glial-cell-line-derived neurotrophic factor mutant mice.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Jul 2007
Yan Yijin, Yamada Kiyofumi, Niwa Minae, Nagai Taku, Nitta Atsumi, Nabeshima Toshitaka
Abstract excerpt
Genetic factors are considered to play an important role in drug dependence/addiction including the development of drug dependence and relapse. With the use of a model of drug self-administration in mutant mice, several specific genes and proteins have been identified as potentially important in the development of drug dependence. In contrast, little is known about the role of specific genes in enduring...
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