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Article

Cannabidiol (CBD) does not reduce cocaine reward or self-administration in a mouse model of schizophrenia genetic susceptibility.

Progress in neuro-psychopharmacology & biological psychiatry - 2 Apr 2026

Chesworth Rose, Watt Georgia, McLemon Erin, Karl Tim

Abstract excerpt

Cannabidiol (CBD) is a non-intoxicating Cannabis sativa plant compound with some preclinical studies reporting efficacy for the treatment of psychiatric disorders, including schizophrenia and substance abuse. Considering that there are high rates of substance use in individuals with schizophrenia, CBD may be effective in the simultaneous treatment of both disorders. However, this exciting possibility has not been...

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Identifiers

PMID: 41881417
DOI: 10.1016/j.pnpbp.2026.111676

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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