Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Premature aging in klotho mutant mice: cause or consequence?

Ageing research reviews - 1 May 2007

Lanske Beate, Razzaque M Shawkat

Abstract excerpt

Suitable mammalian models for aging with a wide range of age-associated pathology are desirable to study molecular mechanisms of human aging. Recent studies have identified that fibroblast growth factor 23 (Fgf-23) null mice and klotho hypomorphs could generate multiple premature aging-like featu...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging, Premature
Share to Fibroblast Growth Factor-23
Share to Fibroblast Growth Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glucuronidase

Share to Klotho Proteins

Share to Mutation

Share to Signal Transduction

Source

Open in PubMed Open full text

Identifiers

PMID: 17353153
DOI: 10.1016/j.arr.2007.02.002
PMCID: PMC2896497

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17353153-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Premature aging in klotho mutant mice: cause or consequence?PMID 17353153Read ↗

Premature aging-like phenotype in fibroblast growth factor 23 null mice is a vitamin D-mediated process.Semantic proximity Read ↗

Hypervitaminosis D and premature aging: lessons learned from Fgf23 and Klotho mutant miceSemantic proximity Read ↗

Amelioration of the premature ageing-like features of Fgf-23 knockout mice by genetically restoring the systemic actions of FGF-23.Semantic proximity Read ↗

Klotho and aging.Semantic proximity Read ↗

Toward a better understanding of Klotho.Semantic proximity Read ↗

The Klotho gene family and the endocrine fibroblast growth factorsSemantic proximity Read ↗

The Antisenescence Protein Klotho Is Necessary for FGF23-Induced PhosphaturiaSemantic proximity Read ↗

Premature aging in vitamin D receptor mutant mice.Semantic proximity Read ↗

Klotho: a fundamental regulator of aging.Semantic proximity Read ↗

The secreted Klotho protein restores phosphate retention and suppresses accelerated aging in Klotho mutant mice.Semantic proximity Read ↗

In vivo genetic evidence for klotho-dependent, fibroblast growth factor 23 (Fgf23) -mediated regulation of systemic phosphate homeostasis.Semantic proximity Read ↗

The FGF23/KLOTHO Regulatory Network and Its Roles in Human Disorders.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.