Article
Digital quantification of mutant DNA in cancer patients.
Current opinion in oncology - 1 Jan 2007
Diehl Frank, Diaz Luis A
Abstract excerpt
PURPOSE OF REVIEW: The accumulation of somatic mutations is the major driving force for tumorigenesis. These mutations uniquely differentiate tumor cells from their normal counterparts. Mutations within tumor cells and mutant DNA released by tumor cells into blood, lymph, stool, tissues and other bodily compartments can thereby be used for cancer detection. Here we discuss technologies available for the detection...
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