Article
Circulating cell-free nucleic acids as biomarkers in colorectal cancer screening and diagnosis.
Expert review of molecular diagnostics - 1 Jan 2016
Tóth Kinga, Barták Barbara Kinga, Tulassay Zsolt, Molnár Béla
Abstract excerpt
Screening methods for the most frequent diagnosed malignant tumor, colorectal cancer (CRC), have limitations. Circulating cell-free DNA (cfDNA) analysis came into focus as a potential screening test for CRC. Detection of epigenetic and genetic alterations of cfDNA as DNA methylation or DNA mutations and related ribonucleic acids may improve cancer detection based on unique, CRC-specific patterns. In this review...
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