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Article

Circulating tumor DNA detectable in early- and late-stage colorectal cancer patients.

Bioscience reports - 31 Aug 2018

Yang Ying-Chi, Wang Dong, Jin Lan, Yao Hong-Wei, Zhang Jing-Hui, Wang Jin, Zhao Xiao-Mu, Shen Chun-Ying, Chen Wei, Wang Xue-Liang, Shi Rong, Chen Si-Yi, Zhang Zhong-Tao

Abstract excerpt

Characterization, diagnosis, and treatment of colorectal cancers (CRC) is difficult due to limited biopsy information, impracticality of repeated biopsies, and cancer biomarker fallibility. Circulating tumor DNA (ctDNA) has recently been investigated as a non-invasive way to gain representative gene mutations in tumors, in addition to monitoring disease progression and response to treatment. We analyzed ctDNA...

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Identifiers

PMID: 29914973
DOI: 10.1042/BSR20180322
PMCID: PMC6066652

Genes

APC
EGFR

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