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Article

Lack of influence of GTP cyclohydrolase gene (GCH1) variations on pain sensitivity in humans.

Molecular pain - 7 Mar 2007

Kim Hyungsuk, Dionne Raymond A

Abstract excerpt

OBJECTIVES: To assess the effect of variations in GTP cyclohydrolase gene (GCH1) on pain sensitivity in humans. METHODS: Thermal and cold pain sensitivity were evaluated in a cohort of 735 healthy volunteers. Among this cohort, the clinical pain responses of 221 subjects after the surgical removal of impacted third molars were evaluated. Genotyping was done for 38 single nucleotide polymorphisms (SNPs) whose...

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Identifiers

PMID: 17343757
DOI: 10.1186/1744-8069-3-6
PMCID: PMC1821314

Genes

GCH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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