Article
Systems analysis of energy metabolism elucidates the affected respiratory chain complex in Leigh's syndrome.
Molecular genetics and metabolism - 1 May 2007
Vo Thuy D, Paul Lee W N, Palsson Bernhard O
Abstract excerpt
Leigh's syndrome is a complex neurological disease with little known correlation between causes and symptoms. Mutations in pyruvate dehydrogenase and electron transport chain complexes have been associated with this syndrome, although the identification of affected enzymes is difficult, if not im...
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