Article

Inhibition of mitochondrial respiration impairs nutrient consumption and metabolite transport in human retinal pigment epithelium

2020-05-11

Abstract excerpt

<h4>ABSTRACT</h4> Mitochondrial respiration in mammalian cells not only generates ATP to meet their own energy needs but also couples with biosynthetic pathways to produce metabolites that can be exported to support neighboring cells. However, how defects in mitochondrial respiration influence these biosynthetic and exporting pathways remains poorly understood. Mitochondrial dysfunction in retinal pigment epithel...

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Literature Corpus work: 8be48b38-4062-54fa-9e65-7457e2075bbe
DOI: 10.1101/2020.05.11.086827

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