Article
Cellular automaton simulation examining progenitor hierarchy structure effects on mammary ductal carcinoma in situ.
Journal of theoretical biology - 7 Jun 2007
Bankhead Armand, Magnuson Nancy S, Heckendorn Robert B
Abstract excerpt
A computer simulation is used to model ductal carcinoma in situ, a form of non-invasive breast cancer. The simulation uses known histological morphology, cell types, and stochastic cell proliferation to evolve tumorous growth within a duct. The ductal simulation is based on a hybrid cellular automaton design using genetic rules to determine each cell's behavior. The genetic rules are a mutable abstraction that...
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