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Article

A hybrid agent-based model of the developing mammary terminal end bud.

Journal of theoretical biology - 21 Oct 2016

Butner Joseph D, Chuang Yao-Li, Simbawa Eman, Al-Fhaid A S, Mahmoud S R, Cristini Vittorio, Wang Zhihui

Abstract excerpt

Mammary gland ductal elongation is spearheaded by terminal end buds (TEBs), where populations of highly proliferative cells are maintained throughout post-pubertal organogenesis in virgin mice until the mammary fat pad is filled by a mature ductal tree. We have developed a hybrid multiscale agent-based model to study how cellular differentiation pathways, cellular proliferation capacity, and endocrine and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27475843
DOI: 10.1016/j.jtbi.2016.07.040
PMCID: PMC5010453

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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