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Article

Human anulus fibrosis and nucleus pulposus cells of the intervertebral disc: effect of degeneration and culture system on cell phenotype.

Spine - 15 Dec 2005

Kluba Torsten, Niemeyer Thomas, Gaissmaier Christoph, Gründer Tatiana

Abstract excerpt

STUDY DESIGN: Human intervertebral disc cells were harvested from patients with adolescent idiopathic scoliosis (AIS) and from donors with degenerative disc disease. Anulus fibrosis (AF) was separated from nucleus pulposus (NP), and cells were cultured separately in two different cell culture models. OBJECTIVES: To investigate changes in gene expression of human disc cells during in vitro expansion and to...

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PMID: 16371897
DOI: 10.1097/01.brs.0000192204.89160.6d

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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