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Article

Polymorphisms in the Paan-AG promoter influence NF-kappaB binding and transcriptional activity.

Immunogenetics - 1 May 2007

Langat Daudi K, Morales Pedro J, Omwandho Charles O, Fazleabas Asgerally T

Abstract excerpt

The human leukocyte antigen-G (HLA-G) gene encodes a protein that is highly expressed at the human maternal-fetal interface during pregnancy and may be critical to the survival of the semiallogenic fetus. A unique feature of this gene is a 13-bp deletion in the proximal promoter that renders it unresponsive to transactivation by the nuclear factor-kappaB (NF-kappaB). We previously showed that the proximal...

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Identifiers

PMID: 17333165
DOI: 10.1007/s00251-007-0203-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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