Article
The enhancement of homogenous mass extension reaction: comparison of two enzymes.
Molecular and cellular probes - 1 Jun 2007
Tikka-Kleemola Päivi, Hämäläinen Eija, Tuomainen Kari, Suvela Minna, Artma Agu, Kahre Olev, Wessman Maija, Palotie Aarno, Silander Kaisa
Abstract excerpt
Reliable and efficient PCR and extension reactions using standardized procedures are key elements for successful single nucleotide polymorphism (SNP) genotyping projects. To improve the cost efficiency and overall performance of SNP genotyping we evaluated two commercial thermostable DNA polymerases used for the extension reaction in the homogeneous mass extension MassARRAY genotyping system. The aim was to study...
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