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Article

Control of signaling in a MAP-kinase pathway by an RNA-binding protein.

PloS one - 28 Feb 2007

Prinz Susanne, Aldridge Christine, Ramsey Stephen A, Taylor R James, Galitski Timothy

Abstract excerpt

Signaling-protein mRNAs tend to have long untranslated regions (UTRs) containing binding sites for RNA-binding proteins regulating gene expression. Here we show that a PUF-family RNA-binding protein, Mpt5, represses the yeast MAP-kinase pathway controlling differentiation to the filamentous form. Mpt5 represses the protein levels of two pathway components, the Ste7 MAP-kinase kinase and the Tec1 transcriptional...

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Identifiers

PMID: 17327913
DOI: 10.1371/journal.pone.0000249
PMCID: PMC1803019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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