Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HLA-DRB1*0404 is strongly associated with anticalpastatin antibodies in rheumatoid arthritis.

Annals of the rheumatic diseases - 1 Dec 2007

Auger Isabelle, Roudier Chantal, Guis Sandrine, Balandraud Nathalie, Roudier Jean

Abstract excerpt

OBJECTIVE: To test whether HLA-DR alleles influence the production of particular autoantibodies in rheumatoid arthritis (RA) patients, we screened synovial proteins with sera of RA patients homozygous for different HLA-DR alleles by using 2D blots. We found that sera of RA patients homozygous for HLA-DRB1*0404 recognised a 100-kDa synovial protein identified as calpastatin. We studied B and T cell epitopes on...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arthritis, Rheumatoid
Share to Autoantibodies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Calcium-Binding Proteins

Share to Electrophoresis, Gel, Two-Dimensional

Share to Epitopes

Share to HLA-DR Antigens

Share to HLA-DRB1 Chains

Share to Synovial Membrane

Source

Open in PubMed Open full text

Identifiers

PMID: 17324966
DOI: 10.1136/ard.2006.067231
PMCID: PMC2095311

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HLA-DRB1*0404 is strongly associated with anticalpastatin antibodies in rheumatoid arthritis.PMID 17324966Read ↗

HLA-C alleles confer risk for anti-citrullinated peptide antibody-positive rheumatoid arthritis independent of HLA-DRB1 alleles.Semantic proximity Read ↗

A new classification of HLA-DRB1 alleles differentiates predisposing and protective alleles for autoantibody production in rheumatoid arthritis.Semantic proximity Read ↗

Alterations of the synovial T cell repertoire in anti-citrullinated protein antibody-positive rheumatoid arthritis.Semantic proximity Read ↗

A large-scale association study identified multiple HLA-DRB1 alleles associated with ACPA-negative rheumatoid arthritis in Japanese subjects.Semantic proximity Read ↗

Associations between serum anti-CCP antibody, rheumatoid factor levels and HLA-DR4 expression in Hungarian patients with rheumatoid arthritis.Semantic proximity Read ↗

Prevalence of soluble peptidylarginine deiminase 4 (PAD4) and anti-PAD4 antibodies in autoimmune diseases.Semantic proximity Read ↗

Influence of human leucocyte antigen-DRB1 on the susceptibility to rheumatoid arthritis and on the production of anti-cyclic citrullinated peptide antibodies in a Portuguese population.Semantic proximity Read ↗

HLA-DPB1*0201 is associated with particular clinical features of rheumatoid arthritis.Semantic proximity Read ↗

Association of HLA-DR4-Dw15 (DRB1*0405) and DR10 with rheumatoid arthritis in a Spanish population.Semantic proximity Read ↗

Influence of HLA-DR genes on the production of rheumatoid arthritis-specific autoantibodies to citrullinated fibrinogen.Semantic proximity Read ↗

Association of TAP2 polymorphism with rheumatoid arthritis is secondary to allelic association with HLA-DRB1.Semantic proximity Read ↗

Rheumatoid arthritis (RA)-associated HLA-DR alleles form less stable complexes with class II-associated invariant chain peptide than non-RA-associated HLA-DR alleles.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.