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Article

Association of TAP2 polymorphism with rheumatoid arthritis is secondary to allelic association with HLA-DRB1.

Arthritis and rheumatism - 1 Apr 1994

Marsal S, Hall M A, Panayi G S, Lanchbury J S

Abstract excerpt

OBJECTIVE: To study polymorphisms of the newly described TAP2 locus in rheumatoid arthritis (RA) and to analyze their relationship with HLA-DRB1 alleles previously implicated in the development of the disease. METHODS: TAP2 polymorphic residues at 3 sites, Val/Ile-379, Ala/Thr-565, and Ala/Thr-665, were characterized by amplification refractory mutation system polymerase chain reaction in 185 RA patients and 48...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Histocompatibility Antigens Class II

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Source

Identifiers

PMID: 8147927
DOI: 10.1002/art.1780370410

Genes

TAP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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Association of TAP2 polymorphism with rheumatoid arthritis is secondary to allelic association with HLA-DRB1.PMID 8147927Read ↗

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Analysis of the MHC-encoded transporters TAP1 and TAP2 in rheumatoid arthritis: linkage with DR4 accounts for the association with a minor TAP2 allele.Semantic proximity Read ↗

Polymorphisms in the TAP2 gene and their association with rheumatoid arthritis.Semantic proximity Read ↗

Peptide transporter genes (TAP) polymorphisms and genetic susceptibility to rheumatoid arthritis.Semantic proximity Read ↗

Polymorphism of human major histocompatibility complex-encoded transporter associated with antigen processing (TAP) genes and susceptibility to juvenile rheumatoid arthritis.Semantic proximity Read ↗

Association between protein tyrosine phosphatase 22 variant R620W in conjunction with the HLA–DRB1 shared epitope and humoral autoimmunity to an immunodominant epitope of cartilage‐specific type II collagen in early rheumatoid arthritisSemantic proximity Read ↗

Association of TAP2 gene polymorphisms in Chinese patients with rheumatoid arthritis.Semantic proximity Read ↗

HLA-DPB1*0201 is associated with particular clinical features of rheumatoid arthritis.Semantic proximity Read ↗

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