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Article

Influence of HLA-DR genes on the production of rheumatoid arthritis-specific autoantibodies to citrullinated fibrinogen.

Arthritis and rheumatism - 1 Nov 2005

Auger Isabelle, Sebbag Mireille, Vincent Christian, Balandraud Nathalie, Guis Sandrine, Nogueira Leonor, Svensson Björn, Cantagrel Alain, Serre Guy, Roudier Jean

Abstract excerpt

OBJECTIVE: Antibodies directed against citrullinated fibrinogen are highly specific for rheumatoid arthritis (RA). This study was undertaken to test whether RA-associated HLA-DR alleles are associated with anti-citrullinated fibrinogen in RA patient sera and whether replacement of arginyl by citr...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16255019
DOI: 10.1002/art.21391

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16255019-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Influence of HLA-DR genes on the production of rheumatoid arthritis-specific autoantibodies to citrullinated fibrinogen.PMID 16255019Read ↗

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Multiple antibody reactivities to citrullinated antigens in sera from patients with rheumatoid arthritis: association with HLA-DRB1 alleles.Semantic proximity Read ↗

Autoimmunity to specific citrullinated proteins gives the first clues to the etiology of rheumatoid arthritis.Semantic proximity Read ↗

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HLA and anti-citrullinated protein antibodies: Building blocks in RA.Semantic proximity Read ↗

The role of posttranslational modifications in generating neo-epitopes that bind to rheumatoid arthritis-associated HLA-DR alleles and promote autoimmune T cell responses.Semantic proximity Read ↗

A molecular basis for the association of the <i>HLA-DRB1</i> locus, citrullination, and rheumatoid arthritisSemantic proximity Read ↗

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