Article
Gene expression profiling in C57BL/6J and A/J mouse inbred strains reveals gene networks specific for brain regions independent of genetic background.
BMC genomics - 11 Jan 2010
de Jong Simone, Fuller Tova F, Janson Esther, Strengman Eric, Horvath Steve, Kas Martien J H, Ophoff Roel A
Abstract excerpt
BACKGROUND: We performed gene expression profiling of the amygdala and hippocampus taken from inbred mouse strains C57BL/6J and A/J. The selected brain areas are implicated in neurobehavioral traits while these mouse strains are known to differ widely in behavior. Consequently, we hypothesized that comparing gene expression profiles for specific brain regions in these strains might provide insight into the...
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