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Article

Quantitative evaluation of human delta opioid receptor desensitization using the operational model of drug action.

Molecular pharmacology - 1 May 2007

Navratilova Edita, Waite Sue, Stropova Dagmar, Eaton Miriam C, Alves Isabel D, Hruby Victor J, Roeske William R, Yamamura Henry I, Varga Eva V

Abstract excerpt

Agonist-mediated desensitization of the opioid receptors is thought to function as a protective mechanism against sustained opioid signaling and therefore may prevent the development of opioid tolerance. However, the exact molecular mechanism of opioid receptor desensitization remains unresolved...

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Source

Identifiers

PMID: 17322005
DOI: 10.1124/mol.106.030023

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17322005-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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