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Article

Estimation of epistasis among finite polygenic loci for complex traits with a mixed model using Gibbs sampling.

Journal of biomedical informatics - 1 Oct 2007

Lee Chaeyoung, Park Jungdae

Abstract excerpt

Epistasis among loci is important factor behind the expression of many complex traits, but many analyses have ruled out its possibility. A method to estimate epistasis was introduced with a mixed model using Gibbs sampling (MMGS). The posterior mean estimate for every possible genotype combined from multiple loci was calculated as the mean of the conditional expected values of the parameters in post warming-up...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17321801
DOI: 10.1016/j.jbi.2007.01.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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