Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Induction of epithelial to mesenchymal transition in PMC42-LA human breast carcinoma cells by carcinoma-associated fibroblast secreted factors.

Breast cancer research : BCR - 1 Jan 2007

Lebret Stephanie C, Newgreen Donald F, Thompson Erik W, Ackland M Leigh

Abstract excerpt

BACKGROUND: Breast carcinoma is accompanied by changes in the acellular and cellular components of the microenvironment, the latter typified by a switch from fibroblasts to myofibroblasts. METHODS: We utilised conditioned media cultures, Western blot analysis and immunocytochemistry to investigate the differential effects of normal mammary fibroblasts (NMFs) and mammary cancer-associated fibroblasts (CAFs) on the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast Neoplasms
Share to Carcinoma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Differentiation

Share to Culture Media

Share to Fibroblasts

Share to Phenotype

Share to Tumor Cells, Cultured

Source

Open in PubMed Open full text

Identifiers

PMID: 17311675
DOI: 10.1186/bcr1656
PMCID: PMC1851381

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Induction of epithelial to mesenchymal transition in PMC42-LA human breast carcinoma cells by carcinoma-associated fibroblast secreted factors.PMID 17311675Read ↗

Myoepithelial molecular markers in human breast carcinoma PMC42-LA cells are induced by extracellular matrix and stromal cells.Semantic proximity Read ↗

Carcinoma‐associated fibroblasts: Non‐neoplastic tumour‐promoting mesenchymal cellsSemantic proximity Read ↗

Cellular changes involved in conversion of normal to malignant breast: importance of the stromal reactionSemantic proximity Read ↗

Carcinoma-associated fibroblasts are a rate-limiting determinant for tumour progressionSemantic proximity Read ↗

Breast fibroblasts modulate early dissemination, tumorigenesis, and metastasis through alteration of extracellular matrix characteristics.Semantic proximity Read ↗

Effects of activated fibroblasts on phenotype modulation, EGFR signalling and cell cycle regulation in OSCC cells.Semantic proximity Read ↗

Fibroblast-Derived Extracellular Matrices: An Alternative Cell Culture System That Increases Metastatic Cellular PropertiesSemantic proximity Read ↗

Breast fibroblasts in both cancer and normal tissues induce phenotypic transformation of breast cancer stem cells: a preliminary studySemantic proximity Read ↗

Breast Carcinoma–Associated Fibroblasts and Their Counterparts Display Neoplastic-Specific ChangesSemantic proximity Read ↗

Mammary fibroblasts regulate morphogenesis of normal and tumorigenic breast epithelial cells by mechanical and paracrine signals.Semantic proximity Read ↗

Novel multicellular organotypic models of normal and malignant breast: tools for dissecting the role of the microenvironment in breast cancer progression.Semantic proximity Read ↗

Understanding the impact of 2D and 3D fibroblast cultures on in vitro breast cancer models.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.