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Article

Novel multicellular organotypic models of normal and malignant breast: tools for dissecting the role of the microenvironment in breast cancer progression.

Breast cancer research : BCR - 1 Jan 2009

Holliday Deborah L, Brouilette Kellie T, Markert Anja, Gordon Linda A, Jones J Louise

Abstract excerpt

INTRODUCTION: There is increasing recognition of the role of the microenvironment in the control of both normal and tumour cell behaviour. In the breast, myoepithelial cells and fibroblasts can influence tumour cell behaviour, with myoepithelial cells exhibiting a broad tumour-suppressor activity while fibroblasts frequently promote tumour growth and invasion. This study describes the development of...

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Identifiers

PMID: 19152687
DOI: 10.1186/bcr2218
PMCID: PMC2687706

Genes

HGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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