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Article

Cellular changes involved in conversion of normal to malignant breast: importance of the stromal reaction

1 Jan 1996

Abstract excerpt

Reciprocal interactions between epithelium and mesenchyme mediate crucial aspects of embryonic development and direct the coordinated organogenesis, correct spatial orientation, and the timely expression of functional activity consistent with physiological demands. The mesenchymal equivalent in the adult organism is the stroma, i.e., the loose connective tissue that is separated from the epithelial compartment by...

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PMID: 8592733
DOI: 10.1152/physrev.1996.76.1.69

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