Article
Cells surviving infection by human immunodeficiency virus type 1: vif or vpu mutants produce non-infectious or markedly less cytopathic viruses.
The Journal of general virology - 1 Jan 1992
Kishi M, Nishino Y, Sumiya M, Ohki K, Kimura T, Goto T, Nakai M, Kakinuma M, Ikuta K
Abstract excerpt
Under conditions in which a clonal cell line (M10) isolated from a human T cell lymphotrophic virus type I-transformed MT-4 cell line was completely killed by infection with wild-type human immunodeficiency virus type 1 (HIV-1), equivalent M10 cells survived infection with HIV-1 vif, vpr or vpu m...
Topics
- Blotting, Northern
- Blotting, Southern
- Cell Line, Transformed
- Cell Survival
- Cytopathogenic Effect, Viral
- DNA, Viral
- Fluorescent Antibody Technique
- Gene Products, env
- Gene Products, gag
- Genes, vif
- Genes, vpu
- HIV-1
- Humans
- Kinetics
- Microscopy, Electron