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Article

Phenotypically Vif- human immunodeficiency virus type 1 is produced by chronically infected restrictive cells.

Journal of virology - 1 Mar 1997

Bouyac M, Rey F, Nascimbeni M, Courcoul M, Sire J, Blanc D, Clavel F, Vigne R, Spire B

Abstract excerpt

The permissivity of CD4+ transformed T cells for the replication of human immunodeficiency virus type 1 (HIV-1) vif mutants varies widely between different cell lines. Mutant vif-negative viruses propagate normally in permissive CD4+ cell lines but are unable to establish a productive infection i...

Topics

Cell Line
Gene Deletion
Gene Products, gag
Gene Products, vif
HIV Core Protein p24
HIV Envelope Protein gp120
HIV Reverse Transcriptase
HIV-1
HeLa Cells
Humans
Phenotype
Protein Precursors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Tumor Cells, Cultured

vif Gene Products, Human Immunodeficiency Virus

Source

Open in PubMed Open full text

Identifiers

PMID: 9032385
DOI: 10.1128/JVI.71.3.2473-2477.1997
PMCID: PMC191358

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9032385-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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