Article
Role of PBP1 in cell division of Staphylococcus aureus.
Journal of bacteriology - 1 May 2007
Pereira S F F, Henriques A O, Pinho M G, de Lencastre H, Tomasz A
Abstract excerpt
We constructed a conditional mutant of pbpA in which transcription of the gene was placed under the control of an IPTG (isopropyl-beta-D-thiogalactopyranoside)-inducible promoter in order to explore the role of PBP1 in growth, cell wall structure, and cell division. A methicillin-resistant strain and an isogenic methicillin-susceptible strain, each carrying the pbpA mutation, were unable to grow in the absence of...
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