Article
Association of TGF-beta1, IL-4 and IL-13 gene polymerphisms with asthma in a Chinese population.
Asian Pacific journal of allergy and immunology - 1 Sept 2011
Yang Xue-Xi, Li Fen-Xia, Wu Ying-Shong, Wu Dong, Tan Jia-Yu, Li Ming
Abstract excerpt
BACKGROUND: Asthma is a common respiratory disease caused by genetic and environmental factors. It has been suggested that TGF-beta1, IL-4 and IL-13 play important roles in asthma. OBJECTIVES: We attempted to confirm the roles of TGF-beta1, IL-4 and IL-13 polymorphisms in asthma in a Chinese population. METHODS: Five SNPs (rs1800469, rs2241712, rs2070874, rs20541 and rs1800925) in TGF-beta1, IL-4 and IL-13 were...