Article
CD23 shedding: requirements for substrate recognition and inhibition by dipeptide hydroxamic acids.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] - 1 Feb 2002
Mayer R J, Flamberg P L, Katchur S R, Bolognese B J, Smith D G, Marolewski A E, Marshall L A, Faller A
Abstract excerpt
CD23 (low affinity IgE receptor, FcepsilonRII) is expressed as a Type II extracellular protein on a variety of cells such as B cells, monocytes and macrophages and is cleaved from the cell surface to generate several distinct fragments. The expression of CD23 on the cell surface as well as the generation of soluble fragments of CD23 has been shown to be involved in regulation of IgE synthesis. CD23 is released...
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