Article
From silent genes to noisy populations-dialogue between the genotype and phenotypes of antigenic variation.
The Journal of eukaryotic microbiology - 1 Jan 2000
Marcello Lucio, Barry J David
Abstract excerpt
African trypanosomes evade humoral immunity through antigenic variation whereby, they switch expression of the variant surface glycoprotein (VSG) gene encoding their glycoprotein surface coat. Switching proceeds by duplication from an archive of silent VSG genes into a transcriptionally active lo...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
