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Article

Pharmacogenetic interactions of three candidate gene polymorphisms with ACE-inhibitors or beta-blockers and the risk of atherosclerosis.

British journal of clinical pharmacology - 1 Jul 2007

Schelleman H, Klungel O H, Witteman J C M, Hofman A, van Duijn C M, de Boer A, Stricker B H Ch

Abstract excerpt

AIMS: To investigate whether the angiotensin-converting enzyme (ACE) insertion/deletion (I/D), angiotensinogen M235T or angiotensin II receptor type 1 573C/T polymorphism modify the risk of atherosclerosis associated with beta-blocker or ACE-inhibitor therapy. METHODS: Data were used from the Rotterdam Study, a population-based prospective cohort study in the Netherlands, which started in 1990 and included 7983...

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Identifiers

PMID: 17298481
DOI: 10.1111/j.1365-2125.2007.02848.x
PMCID: PMC2000614

Genes

ACE
AGT

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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