Article
A study of gene--environment interaction on the gene for angiotensin converting enzyme: a combined functional and population based approach.
Journal of medical genetics - 1 Feb 2004
Sayed-Tabatabaei F A, Schut A F C, Hofman A, Bertoli-Avella A M, Vergeer J, Witteman J C M, van Duijn C M
Abstract excerpt
INTRODUCTION: Studies on the role of the insertion/deletion (I/D) polymorphism of the gene coding for angiotensin converting enzyme (ACE) in atherosclerosis have been inconsistent. In a meta-analysis, we recently showed that this relationship is stronger in high risk populations. In this paper, we used a combined functional and population based approach to investigate the gene-environment interaction of the ACE...
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