Article
Drug-gene interaction between the insertion/deletion polymorphism of the angiotensin-converting enzyme gene and antihypertensive therapy.
The Annals of pharmacotherapy - 1 Feb 2006
Schelleman Hedi, Klungel Olaf H, van Duijn Cornelia M, Witteman Jacqueline C M, Hofman Albert, de Boer Anthonius, Stricker Bruno H Ch
Abstract excerpt
BACKGROUND: Despite the availability of a variety of effective drugs, inadequate control of blood pressure is common. There are some indications that the angiotensin-converting enzyme (ACE) gene modifies the response to antihypertensive drugs, but the results have been inconclusive. OBJECTIVE: To...
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