Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Modification of the coronary artery disease risk associated with the presence of traditional risk factors by insertion/deletion polymorphism of the ACE gene.

Genetic testing - 1 Jan 2007

Niemiec Pawel, Zak Iwona, Wita Krystian

Abstract excerpt

Cigarette smoking, hypercholesterolemia, and obesity influence the renin-angiotensin system (RAS) functions including an increased synthesis of the angiotensin I converting enzyme (ACE). Thus in the present work we explore the interactions of the ACE gene insertion/deletion (I/D) polymorphism and traditional risk factors. The study cohort included 341 subjects composed of 172 patients with angiographically...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cohort Studies
Share to Coronary Disease
Share to Hypercholesterolemia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to INDEL Mutation

Share to Peptidyl-Dipeptidase A

Share to Polymorphism, Genetic

Share to Risk Factors

Share to Smoking

Source

Identifiers

PMID: 18294050
DOI: 10.1089/gte.2007.0005

Genes

ACE
CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Modification of the coronary artery disease risk associated with the presence of traditional risk factors by insertion/deletion polymorphism of the ACE gene.PMID 18294050Read ↗

Combined "pro-atherosclerotic" variants of the ACE and APOE genes increase the risk of the coronary artery disease associated with the presence of cigarette smoking.Semantic proximity Read ↗

Traditional risk factors and angiotensin-converting enzyme insertion/deletion gene polymorphism in coronary artery disease.Semantic proximity Read ↗

The Effect of ACE I/D Polymorphisms Alone and With Concomitant Risk Factors on Coronary Artery Disease.Semantic proximity Read ↗

Effects of ACE polymorphisms and other risk factors on the severity of coronary artery disease.Semantic proximity Read ↗

Impacts of ACE insertion/deletion variant on cardiometabolic risk factors, premature coronary artery disease, and severity of coronary lesions.Semantic proximity Read ↗

The D allele of the angiotensin-converting enzyme gene contributes towards blood LDL-cholesterol levels and the presence of hypertension.Semantic proximity Read ↗

Synergistic effects of angiotensin-converting enzyme and angiotensin-II type 1 receptor gene polymorphisms on risk of myocardial infarction.Semantic proximity Read ↗

Association of ACE I/D polymorphism with cardiovascular risk factors.Semantic proximity Read ↗

Angiotensin I-converting enzyme gene polymorphism enhances the effect of hypercholesterolemia on the risk of coronary heart disease in a general Japanese population: the hisayama study.Semantic proximity Read ↗

Angiotensin-converting enzyme genotype and peripheral arterial disease in diabetic patients.Semantic proximity Read ↗

Systematic review and meta-analysis of ACE insertion/deletion variant on cardiometabolic profile, premature coronary artery disease and severity of coronary lesionsSemantic proximity Read ↗

Association of angiotensin-converting enzyme insertion/deletion polymorphism with obesity, cardiovascular risk factors and exercise-mediated changes in Korean women.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.