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Article

Ultraviolet radiation stimulates expression of Snail family transcription factors in keratinocytes

12 Feb 2007

Abstract excerpt

The related zinc finger transcription factors Slug and Snail modulate epithelial mesenchymal transformation (EMT), the conversion of sessile epithelial cells into migratory fibroblast-like cells. EMT occurs during development, wound healing, and tumor progression. Growth factors, acting through mitogen-activated protein kinase (MAPK) cascades, regulate expression of Slug and Snail. Expression of Snail family...

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PMID: 17295233
DOI: 10.1002/mc.20257

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Related research

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Ultraviolet radiation stimulates expression of Snail family transcription factors in keratinocytesPMID 17295233Read ↗

UV irradiation induces Snail expression by AP-1 dependent mechanism in human skin keratinocytesSemantic proximity Read ↗

Ultraviolet Irradiation Alters Transforming Growth Factor β/Smad Pathway in Human Skin In VivoSemantic proximity Read ↗

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Non-canonical functions of SNAIL drive context-specific cancer progressionSemantic proximity Read ↗

Slug is upregulated during wound healing and regulates cellular phenotypes in corneal epithelial cells.Semantic proximity Read ↗

RhoB Protects Human Keratinocytes from UVB-induced Apoptosis through Epidermal Growth Factor Receptor SignalingSemantic proximity Read ↗

Regulation of p63 Isoforms by Snail and Slug Transcription Factors in Human Squamous Cell CarcinomaSemantic proximity Read ↗

UVB radiation induces expression of HIF-1alpha and VEGF through the EGFR/PI3K/DEC1 pathway.Semantic proximity Read ↗

Ultraviolet B-induced apoptosis of human skin fibroblasts involves activation of caspase-8 and -3 with increased expression of vimentinSemantic proximity Read ↗

Aberrant expression of the transcription factors snail and slug alters the response to genotoxic stress.Semantic proximity Read ↗

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