Article
Aberrant expression of the transcription factors snail and slug alters the response to genotoxic stress.
Molecular and cellular biology - 1 Sept 2004
Kajita Masahiro, McClinic Karissa N, Wade Paul A
Abstract excerpt
Snail and Slug are closely related transcriptional repressors involved in embryonic patterning during metazoan development. In human cancer, aberrant expression of Snail and/or Slug has been correlated with invasive growth potential, a property primarily attributed to their ability to directly repress transcription of genes whose products are involved in cell-cell adhesion, such as E-cadherin, occludin, and...
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