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Article

mre11S--a yeast mutation that blocks double-strand-break processing and permits nonhomologous synapsis in meiosis.

Genes & development - 1 Sept 1997

Nairz K, Klein F

Abstract excerpt

During meiotic prophase the repair of self-inflicted DNA double-strand break (DSB) damage leads to meiotic recombination in yeast. We employed a genetic screen to specifically characterize cellular functions that become essential after this DSB formation. As a result a new allele of MRE11, termed mre11S (for Separation of functions) was isolated that allows initiation but not processing and repair of meiotic DSBs...

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Source

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Identifiers

PMID: 9303542
DOI: 10.1101/gad.11.17.2272
PMCID: PMC275393

Genes

MRE11
RAD50

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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mre11S--a yeast mutation that blocks double-strand-break processing and permits nonhomologous synapsis in meiosis.PMID 9303542Read ↗

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